I concur with what has been said. Two summers ago we went on a long holiday touring the south of France in an RV we rented from this website and drove that exact route. We flew to Lyon, picked up the RV and then drove via the north of Lyon to Clermont-Ferrand. Of course in an RV we were automatically inclined to avoid city centres as much as possible, but I had also heard a lot about making sure to avoid the rush hour during my research. From Clermont we drove on to Bordeaux and then down to the southern coast, over Toulouse, Montpellier, Marseilles, Nice and finally back up to Lyon. Of course we took our time and made plenty of stops. It was a truly memorable trip and I can only recommend it.